science-news
I was recently at a talk by Devika Narain (Associate professor at Donders), and one of the things she presented was their new dimensionality reduction method called RATS (Riemannian Alignment of Tangent Spaces). For some reason it really tickled my brain, so here I'll go through what the
science-news
Something I keep hearing more around me (and have noticed myself) is that getting funding for your scientific research is getting structurally worse. The number of proposals for a call seems to be going up every round, success rates are dropping, and somewhere in there a researcher's focus
science-news
One of the central questions in neurodegenerative disease revolves around timing. Proteins such as amyloid-β, tau, and α-synuclein are always present inside of our cells, yet for most of our lives they remain stable and perform their normal functions. For some people, usually later in life, these proteins can start
science-news
I was interested in learning about the scientific core of Genmab’s business model. Looking for this, I found two key papers: the 2013 controlled Fab-arm exchange paper and the 2013 scale-up and manufacturing paper. The conceptual origin sits a bit earlier, in the IgG4 literature, where Fab-arm exchange shows
antibody
I have a soft spot for methods that turn messy cell biology into something that is more quantifiable. When a tool works, it helps bring true progress into our understanding of fundamental biology. When it fails, you can lose weeks to cloning, expression quirks, or reagents that behave differently every